New Techniques for the Qualitative and Quantitative Measurement of Naturally-Ocurring Gonadotropin-Releasing Hormone Analogues by Mass Spectrometry

The effect of LH and GnRH analogues on induction of ovulation in Bactrian camel (Camelus bactrianus)

Ovarian follicle response and corpus luteum formation following induction of ovulation using gonadotropin-releasing hormone (GnRH) analogues and luteinizing hormone (LH) in Bactrian camel were characterized. Bactrian camels with a mature follicle (13-19.6 mm) received: 1) natural porcine LH (25 mg, IV, n = 4), 2) Buserelin (20 μg, IV, n = 4) and 3) Alarelin (25 μg, IM, n = 4). Daily ultrasonogr...

TREATMENT OF PRECOCIOUS PUBERTY BY A LONG-ACTING GONADOTROPIN-RELEASING HORMONE ANALOGUE IN CHILDREN

The GnRH analogue has been shown to be effective in the treatment of precocious puberty when given as a daily subcutaneous injection. We studied the effectiveness of a long-acting GnRH analogue, Triptoreline, for the treatment of central precocity, by suppressing gonadotropin and estradiol secretion in three children with true precocious puberty. One month after single dose intramuscular i...

Intermediary role of kisspeptin in the stimulation of gonadotropin-releasing hormone neurons by estrogen in the preoptic area of sheep brain

Introduction: The role of estrogen in the stimulation of gonadotropin-releasing hormone (GnRH) neurons is clear. These neurons do not express estrogen alpha receptors, so other mediator neurons should be present to transmit the positive feedback effect of estrogen to the GnRH neurons. Kisspeptin neurons have an important role in the stimulation of GnRH neurons, so they can be the mediator of...

Hypogonadism induced by luteinising hormone releasing hormone agonist analogues: effects on bone density in premenopausal women.

Resurgence of Minimal Stimulation In Vitro Fertilization with A Protocol Consisting of Gonadotropin Releasing Hormone-Agonist Trigger and Vitrified-Thawed Embryo Transfer

Minimal stimulation in vitro fertilization (mini-IVF) consists of a gentle controlled ovarian stimulation that aims to produce a maximum of five to six oocytes. There is a misbelief that mini-IVF severely compromises pregnancy and live birth rates. An appraisal of the literature pertaining to studies on mini-IVF protocols was performed. The advantages of minimal stimulation protocols are report...